The endothelin axis, which comprises endothelins and their receptors, is thought to have a role in the pathophysiology of tumors, including prostate, ovarian, colon, lung, breast, and kidney tumors. Endothelins are peptides that exert their effects by binding via two G-protein coupled receptors, endothelin receptor A and B (ET-A and ET-B). ET-A and ET-B appear […] Read more

In April 2010, the Icelandic volcano Eyjafjallajökull erupted for more than a week, causing a flood of meltwater to rush down its slopes, and forced the evacuation of 800 people. Icy water flooded the volcano’s vent, chilling and fragmenting the lava into tiny particles of silica and ash, which exploded into an eruption plume towering […] Read more

The F-35 Lightning II, also known as the Joint Strike Fighter (JSF), integrates advanced very low observable stealth into a supersonic – highly agile 5th generation fighter. The capabilities built into the F-35 Lightning II provide the pilot with unprecedented situational awareness and unmatched lethality – and survivability. While each variant (F-35A, F-35B, F-35C) is […] Read more

In days gone by, two brothers, Raul and Johan, who lived on adjoining farms fell into conflict. It was the first serious rift in 35 years of farming side by side in central Germany, sharing machinery, and trading labour and goods as needed without a single problem occurring. However, one autumn, the long collaboration fell […] Read more

#1: Origin of Space and Time From Einstein’s work on general relativity came the recognition that there must be an origin for matter and energy. From Penrose, Hawking, and Ellis’ work came the acknowledgement that there must be an origin for space and time, too. With the knowledge that time has a beginning, and a […] Read more

#2: The Earth as a Fit Habitat About a dozen more parameters, including several atmospheric characteristics, currently are being researched for their sensitivity in the support of life. However, the twenty listed in Table 12.1 in themselves lead safely to the conclusion that much fewer than a trillionth of a percent of all stars will […] Read more

At the time of his death, Eddie was a squat, white haired old man, with a short neck, a barrel chest, thick forearms, and a faded army tattoo on his right shoulder. His legs were thin and veined now, and his left knee, wounded in the war, was ruined by arthritis. He used a cane […] Read more

At the time of his death, Eddie was a squat, white haired old man, with a short neck, a barrel chest, thick forearms, and a faded army tattoo on his right shoulder. His legs were thin and veined now, and his left knee, wounded in the war, was ruined by arthritis. He used a cane […] Read more

This is a story about a man name Eddie and it begins at the end, with Eddie dying in the sun. It might seem strange to start a story with an ending. But all endings are also beginnings. We just don’t know it at the time. The last hour of Eddie’s life was spent, like […] Read more