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At Bayer, a passion for science inspires us to address
many of the health challenges in the world today.

Here, at Bayer’s manufacturing site in Berkeley
California, is where our commitment to the hemophilia
A community begins.

Hemophilia A is a deficiency in clotting factor eight – a
condition that prevents the blood from properly clotting.

The BHK cells were also modified by adding the gene
for a 70-kilodalton human heat shock protein, referred
to as HSP70.

In addition to enhancing the host cell’s resistance to
apoptosis, or programmed cell death, HSP70 also
enhances proper protein folding of Kovaltry™.